Computational Modeling of Biological Systems (SysMod)

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The Computational Modeling of Biological Systems (SysMod) Community Of Special Interest aims at bridging the gap between bioinformatics and systems biology modeling. With advances in genomics these fields have recently started to converge. For example, systems modeling has become more reliant on bioinformatic network inference to build models and has begun to use transcriptomics and proteomics data to train models. More communication between systems modelers and bioinformaticians is needed to further integrate these fields. In particular, more communication between systems modellers and bioinformaticians is needed to build models of whole cells, organs and organisms. Furthermore, the promises of precision medicine lie, in part, on the interplay between bioinformatics-based analysis of patient data and model-based predictions of treatments.

SysMod is a Community of Special Interests (COSI) within the International Society for Computational Biology.


Annual SysMod meeting

The main activity of the SysMod COSI is a meeting part of the ISMB (Intelligent Systems in Molecular Biology, which the annual meeting of the ISCB).

The goal of the SysMod meeting is to foster the integration of systems modeling and bioinformatics by creating a forum for systems modelers and bioinformaticians to discuss common research questions and methods. The meeting will focus on the mathematical modeling of biological systems, and its interactions with bioinformatics. The meeting will cover the full range of methods used in systems modeling, including qualitative and quantitative and dynamical and steady modeling, as well as cover the full range of applications of systems modeling including basic science, bioengineering, and medicine. The first SysMod meeting will focus on areas of systems modeling which are, or could be, deeply integrated with bioinformatics, including logical, rule-based, and constraint-based modeling.

  • 2017 SysMod meeting. SysMod will organise one of the day of the "systems" theme at the next ISMB in July 2017 in Prague.
  • 2016 SysMod meeting. The first meeting took place July 9, 2016 at the ISMB Conference in Orlando, Florida. The meeting featured three keynote talks, seven contributed talks, a community discussion, and a poster session.
  • On July 10th 2016, SysMod jointly organised a special COSI session with the NetBio COSI. The session comprised short presentations of the COSI, 4 talks by renowned speakers and discussions on how to build synergies.

Some of the slides and posters presented at the SysMod meeting can be found on the SysMod channel of F1000.

SysMod mailing list

People interested in the activity of SysMod, can joint the sysmod Google group. This list is for advertisement of relevant scientific meetings, software releases, positions etc. Posting is limited to subscribers, but reading access is unrestricted.


Please see the SysMod Google calendar or download the .ics file.

Organizing committee

More information

Please follow us on Twitter, subscribe to the SysMod Google Group, or contact us at