The Computational Modeling of Biological Systems (SysMod) Community of Special Interest (COSI) of the International Society for Computational Biology (ISCB) external-link is a forum for discussion about the combined use of systems biology modeling and bioinformatics to understand biology and disease. SysMod encompasses all methods used in bioinformatics and systems biology, as well as all biological systems and all applications areas. The main activities of SysMod include an annual meeting at the Intelligent Systems for Molecular Biology (ISMB external-link) conference organized by the ISCB and an online forum external-link.

For more information, or to cite SysMod, see the manuscript:

SysMod: the ISCB community for data-driven computational modelling and multi-scale analysis of biological systems external-link
A. Dräger, T. Helikar, M. Barberis, M. Birtwistle, L. Calzone, C. Chaouiya, J. Hasenauer, J. R. Karr, A. Niarakis, M. Rodríguez Martínez, J. Saez-Rodriguez und J. Thakar
Bioinformatics, btab229, June 24th 2021. DOI external-link

New: SysMod Webinar at ISCB Academy 🔗

Annual meeting

7th Annual SysMod at ISMB 2022 – Madison, WI, United States

The main activity of SysMod is an annual one-day meeting at the annual Intelligent Systems in Molecular Biology (ISMB/ECCB external-link) conference organized by the International Society for Computational Biology (ISCB external-link). The meeting is a forum for discussion about the integration of systems biology and bioinformatics. As such, it includes keynote talks, contributed talks, and poster sessions. The seventh annual SysMod meeting external-link will take place in July 2022 in Madison, WI, United States at the ISMB conference. external-link. Please see the meeting page for more information.


The recording of the first SysMod Webinar at ISCB Academy 🔗 is now available from YouTube external-link.

Google Group

The SysMod Google Group is an forum for discussion among systems biologists and bioinformaticians. Please visit Google Groups external-link to join.


The sixth annual SysMod meeting 🔗 will take place in July 2021, during the ISMB/ECCB conference in Lyon, France external-link.

Twitter feed


Matteo Barberis external-link
University of Surrey, UK

Marc Birtwistle external-link
Clemson University, US

Laurence Calzone external-link
Curie Institute, Paris, FR

Claudine Chaouiya external-link
Aix Marseille University, FR

Andreas Dräger external-link
University of Tübingen, DE

Jan Hasenauer external-link
University of Bonn, DE

Tomáš Helikar external-link
University of Nebraska–Lincoln, US

Jonathan Karr external-link
Icahn School of Medicine at Mount Sinai, US

Anna Niarakis external-link
Université dʼ Evry Val dʼ Essonne, FR

María Rodríguez Martínez external-link
IBM, Zurich Research Laboratory, CH

Julio Saez-Rodriguez external-link
University of Heidelberg, DE

Juilee Thakar external-link
University of Rochester, US

Coordinator alumni

Nicolas Le Novère external-link